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Benzodiazepine Equivalence Table
 


 
  
  

NEVER quit psychiatric medications such as
 benzodiazepines, antidepressants or anti-psychotics cold turkey!!

Benzodiazepine Equivalence Table
(Benzodiazepine Equivalency Table)

Revised June 2002

This Benzodiazepine Equivalence Table is based on the extensive research and clinical experience of Professor C Heather Ashton, DM, FRCP, Emeritus Professor of Clinical Psychopharmacology at the University of Newcastle upon Tyne, England. Sources: NRHA Drug Newsletter, April 1985 and Benzodiazepines: How they Work & How to Withdraw (The Ashton Manual), 2002. The approximate equivalent doses to 10mg diazepam (Valium) are given.  Order the Ashton Manual Click here.

For a discussion of half-lives and equivalencies see also the Benzo FAQ document.

Benzodiazepines1

Half-life (hrs)2
[active metabolite]

Approximately Equivalent
Oral dosages (mg)3

Market Aim4

Alprazolam
(Xanax)

6-12

0.5

a

Bromazepam
(Lexotan)

10-20

5-6

a

Chlordiazepoxide
(Librium)

5-30 [36-200]

25

a

Clobazam
(Frisium)5

12-60

20

a,e

Clonazepam
(Klonopin, Rivotril)5

18-50

0.5

a,e

Clorazepate
(Tranxene)

[36-200]

15

a

Diazepam
(Valium)

20-100 [36-200]

10

a

Estazolam
(ProSom)

10-24

1-2

h

Flunitrazepam
(Rohypnol)

18-26 [36-200]

1

h

Flurazepam
(Dalmane)

[40-250]

15-30

h

Halazepam
(Paxipam)

[30-100]

20

a

Ketazolam
(Anxon)

2

15-30

a

Loprazolam
(Dormonoct)

6-12

1-2

h

Lorazepam
(Ativan)

10-20

1

a

Lormetazepam
(Noctamid)

10-12

1-2

h

Medazepam
(Nobrium)

36-200

10

a

Nitrazepam
(Mogadon)

15-38

10

h

Oxazepam
(Serax, Serenid D)

4-15

20

a

Prazepam
(Centrax)

[36-200]

10-20

a

Quazepam (Doral)

25-100

20

h

Temazepam
(Restoril,
Normison,
Euhypnos)

8-22

20

h

Triazolam
(Halcion)

2

0.5

h

Non-benzodiazepines
with similar effects1, 6

 

 

 

Zaleplon
(Sonata)

2

20

h

Zolpidem
(Ambien, Stilnoct)

2

20

h

Zopiclone
(Zimovane, Imovane)

5-6

15

h

  1. All these drugs are recommended for short-term use only (2-4 weeks maximum).

  2. Half-life: time taken for blood concentration to fall to half its peak value after a single dose. Half-life of active metabolite shown in square brackets. This time may vary considerably between individuals.

  3. These equivalents do not agree with those used by some authors. They are firmly based on clinical experience during switch-over to diazepam at start of withdrawal programs but may vary between individuals.

  4. Market Aim: Although all benzodiazepines have similar actions, they are usually marketed as anxiolytics (a), hypnotics (h) or anticonvulsants (e).

  5. In the UK clobazam (Frisium) and clonazepam (Rivotril) are licensed for use as anti-epileptics only.

  6. These drugs are chemically different from benzodiazepines but have the same effects on the body and act by the same mechanisms.


Battling The Benzos and Ending Dependency
an article by Dr. Terry Neher


Click here to order beCALM'd
A supplement that has been helpful for balancing brain neurotransmitters and easing symptoms of benzodiazepine withdrawal.

Ingredients: 
Calcium 50 mg
Magnesium 25 mg
Vitamin B-6 1.0 mg
Folic Acid 0.1 mg
L-Glutamine 150 mg
DL-Phenylalanine 300 mg
5-HTP 5 mg

 

Learn about Natural CALM
magnesium citrate powder
Helps with insomnia and muscle tension


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"This information is not intended to diagnose, cure, treat,
mitigate, or prevent a disease or illness. Results may vary per person"

Amy Houston
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